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Costeff Syndrome (3-methylglutaconic aciduria type III) is a rare genetic condition causing early-onset optic atrophy along with movement difficulties such as chorea and spasticity later in life. Genetic testing and specialized metabolic/neuro-ophthalmology care for this condition are largely unavailable within Pakistan. Optic Atrophy Treatment Center works with Pakistani families exploring stem cell therapy for the optic nerve component of Costeff Syndrome.
10+
years Experience
years Experience
5000+
Patients treated
Patients treated
100+
Countries served
Countries served
NABH
Guided facility
Guided facility
Why Pakistani Patients Consider This Option
As an extremely rare metabolic-genetic condition, Costeff Syndrome requires specialized diagnostic testing (urine organic acid analysis, genetic testing for the OPA3 gene) that is not widely available within Pakistan. Families often look abroad for both diagnostic confirmation and to explore treatment options for the optic nerve damage.
Meet The Team
Our Eye Specialists
Dr. Pawan
Associate Professor, Vitreo-Retina Surgeon. 10+ Years Experience
Retinal disorders, diabetic retinopathy, and advanced retina procedures. Provides diagnostic evaluation and treatment planning for international patients.
Dr.Pallavee
Senior Consultant Ophthalmologist & Eye Surgeon· 26+ yrs experience
Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.
Dr. Robin
Consultant Ophthalmologist & Eye Surgeon, MD, DO .16+ Years Experience
Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.
How Stem Cell Therapy May Help
Stem cell therapy is studied for its potential to help support optic nerve tissue affected by Costeff Syndrome. It addresses the vision component only — the movement-related features (chorea, spasticity) require ongoing management by a neurologist.
Is This Treatment Right for You?
Suitability depends on the stage and cause of the condition. Before travelling, our team reviews:
01 Genetic or metabolic test results (urine organic acids, OPA3 gene), if available
02 OCT scan and visual field test results
03 Age of onset of vision loss and any movement symptoms
04Current neurology management status, if applicable
What Your Visit Includes
- Remote pre-screening based on reports shared in advance
- In-person evaluation by our ophthalmology and regenerative medicine team
- Diagnostic work-up to confirm disease stage and suitability
- Stem cell therapy administered under medical supervision
- A written follow-up plan your doctor in Pakistan can continue monitoring
- Airport pickup, accommodation assistance, and a dedicated patient coordinator throughout your stay
Travelling from Pakistan — What to Expect
- Visa: India has currently suspended visa services, including medical visas, for Pakistani nationals. This means direct travel from Pakistan to India for treatment is not possible under the present rules. Please contact our team for the latest update, as this position can change.
- Cost guidance: Treatment packages are quoted in USD; approximate Pakistani Rupee (PKR) equivalents are provided on request.
- In the meantime: Our team can carry out a remote review of reports (OCT scan, visual field test, genetic/metabolic results) and provide a written medical opinion, so families have clarity on suitability before any travel becomes possible.
- Language:All consultations and medical reports are provided in English and Urdu.
Reviews
What Our Patients Say
Bunty Singh
Excellent customer service and straight away got some improvement as my eye points stop hurting when i press them so and still on the healing process. Very experienced doctor and lovely people. Happy with it.
Aneeket Kushwah
I came from overseas specifically for treatment. The staff not only assisted me with transport but also made the whole experience hassle-free. The medical service was of the highest standard and I was very secure in Delhi.
Frequently Asked Questions
Will this treat the movement symptoms of Costeff Syndrome?
“No, our evaluation and treatment address the optic nerve/vision component only. Movement-related symptoms should be managed by a neurologist.”
Is genetic confirmation required before travelling?
” It’s helpful if available, but not mandatory — our team can review based on clinical history and OCT/visual field findings.”
Can Pakistani patients currently travel to India for this treatment?
“At present, India’s visa suspension for Pakistani nationals means direct travel is not possible. We recommend starting with a remote report review so you’re ready to proceed as soon as the situation changes.”
