Costeff Syndrome — Treatment in Mexico

Costeff syndrome (3-methylglutaconic aciduria type III) is a rare genetic condition caused by OPA3 gene mutations, causing early-onset optic atrophy along with movement difficulties such as chorea and spasticity later in life. Genetic testing and specialized neuro-ophthalmology evaluation are often limited where families live, which is why many look abroad for a confirming opinion.

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    Why Mexican Patients Consider This Option

    As an extremely rare metabolic-genetic condition, Costeff syndrome requires specific diagnostic testing (urinary organic acid analysis, OPA3 genetic testing) that isn’t widely available everywhere. Families often want both diagnostic confirmation and an honest picture of what can currently be done for the optic nerve component.

    Meet The Team

    Our Eye Specialists

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    Dr. Pawan

    Associate Professor, Vitreo-Retina Surgeon. 10+ Years Experience

    Retinal disorders, diabetic retinopathy, and advanced retina procedures. Provides diagnostic evaluation and treatment planning for international patients.

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    Dr.Pallavee

    Senior Consultant Ophthalmologist & Eye Surgeon· 26+ yrs experience

    Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.

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    Dr. Robin

    Consultant Ophthalmologist & Eye Surgeon, MD, DO .16+ Years Experience

    Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.

    How Care Is Approached

    There is no cure for Costeff syndrome. Our evaluation focuses on confirming disease stage via OCT and visual field testing, and giving families a clear, current picture of the vision component specifically — the movement-related features (chorea, spasticity) remain under ongoing neurology management and are outside what an eye-focused evaluation can address. Where regenerative approaches are discussed, we are explicit that these remain under investigation and are not an established cure.

    Is This Treatment Right for You?

    Suitability depends on the stage and cause of the condition. Before travelling, our team reviews:

    01Genetic or metabolic test results (urine organic acids, OPA3), if available
    02OCT and visual field test results
    03Age of onset of vision loss and movement symptoms
    04</spanCurrent neurology management status, if applicable

    What Your Visit Includes

    • Remote pre-screening based on reports shared in advance
    • In-person evaluation by our ophthalmology and regenerative medicine team
    • Diagnostic work-up to confirm disease stage and suitability
    • Stem cell therapy administered under medical supervision
    • A written follow-up plan your doctor in mexic can continue monitoring

    Travelling from Mexico — What to Expect

    • Visa and appointment logistics vary; our coordinator confirms current requirements before booking
    • Treatment estimates are provided in USD and Mexican Peso equivalents on request
    • All consultations and reports are available in English and Spanish
    Reviews

    What Our Patients Say

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    Bunty Singh

    Excellent customer service and straight away got some improvement as my eye points stop hurting when i press them so and still on the healing process. Very experienced doctor and lovely people. Happy with it.

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    Aneeket Kushwah

    I came from overseas specifically for treatment. The staff not only assisted me with transport but also made the whole experience hassle-free. The medical service was of the highest standard and I was very secure in Delhi.

    Frequently Asked Questions

    Will this treat the movement symptoms of Costeff Syndrome?

    “No, our evaluation and treatment address the optic nerve/vision component only. Movement-related symptoms should be managed by a neurologist.”

    Is genetic confirmation required before travelling?

    ” It’s helpful if available, but not mandatory — our team can review based on clinical history and OCT/visual field findings.”

    Can Mexico patients currently travel to India for this treatment?

    “At present, India’s visa suspension for Mexico nationals means direct travel is not possible. We recommend starting with a remote report review so you’re ready to proceed as soon as the situation changes.”

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