Costeff Syndrome (3-methylglutaconic aciduria type III) is a rare genetic condition causing early-onset optic atrophy along with movement difficulties such as chorea and spasticity later in life. Genetic testing and specialized metabolic/neuro-ophthalmology care for this condition are essentially unavailable within Nigeria. Optic Atrophy Treatment Center works with Nigerian families exploring stem cell therapy for the optic nerve component of Costeff Syndrome.
As an extremely rare metabolic-genetic condition, Costeff Syndrome requires specialized diagnostic testing (urine organic acid analysis, genetic testing for the OPA3 gene) that is not available within Nigeria. Families often travel abroad for both diagnostic confirmation and to explore treatment options for the optic nerve damage.

Associate Professor, Vitreo-Retina Surgeon. 10+ Years Experience

Senior Consultant Ophthalmologist & Eye Surgeon· 26+ yrs experience

Consultant Ophthalmologist & Eye Surgeon, MD, DO .16+ Years Experience
Stem cell therapy is studied for its potential to help support optic nerve tissue affected by Costeff Syndrome. It addresses the vision component only — the movement-related features (chorea, spasticity) require ongoing management by a neurologist.
Suitability depends on the stage and cause of the condition. Before travelling, our team reviews:

I feel very happy and I am very much satisfied with stem cell cure india services and my daughter just took stem cell treatment for eye genetic disease called RP (Bardet Biedl Syndrome) and we are hopeful to see some good improvement.

Excellent customer service and straight away got some improvement as my eye points stop hurting when i press them so and still on the healing process. Very experienced doctor and lovely people. Happy with it
” No, our evaluation and treatment address the optic nerve/vision component only. Movement-related symptoms should be managed by a neurologist.”
“It’s helpful if available, but not mandatory — our team can review based on clinical history and OCT/visual field findings.”
” OCT scan, visual field test, any metabolic/genetic test results, and a summary of when vision loss and movement symptoms began.”

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